Yanzhong Wang Selected Research

Nicotinamide N-Methyltransferase

1/2021	Curcumin Reverses NNMT-Induced 5-Fluorouracil Resistance via Increasing ROS and Cell Cycle Arrest in Colorectal Cancer Cells.
1/2021	Overexpression of Nicotinamide N-methyltransferase mainly covers stroma of colorectal cancer and correlates with unfavorable survival by its product 1-MNA.
1/2020	Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells.
1/2019	Nicotinamide N-methyltransferase enhances chemoresistance in breast cancer through SIRT1 protein stabilization.
7/2016	Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway.
12/2014	Nicotinamide N-methyltransferase enhances the capacity of tumorigenesis associated with the promotion of cell cycle progression in human colorectal cancer cells.
1/2014	Down-regulation of nicotinamide N-methyltransferase induces apoptosis in human breast cancer cells via the mitochondria-mediated pathway.

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Yanzhong Wang Research Topics

Disease

17	Neoplasms (Cancer) 01/2022 - 06/2005
8	Breast Neoplasms (Breast Cancer) 11/2020 - 01/2007
6	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 12/2014
4	Stroke (Strokes) 01/2022 - 10/2018
3	Type 2 Diabetes Mellitus (MODY) 05/2022 - 12/2018
3	Infections 06/2016 - 05/2011
2	Macular Degeneration (Age-Related Maculopathy) 01/2022 - 11/2016
2	Leukemia 01/2022 - 09/2009
2	Hypertension (High Blood Pressure) 01/2022 - 10/2018
2	Substance-Related Disorders (Drug Abuse) 01/2022 - 12/2021
2	Obesity 01/2022 - 12/2021
2	Lymphatic Metastasis 01/2021 - 07/2020
2	Acute Coronary Syndrome 01/2021 - 01/2019
2	Atrial Fibrillation 10/2018 - 06/2016
2	Hepatitis B 02/2013 - 03/2012
2	Communicable Diseases (Infectious Diseases) 01/2013 - 02/2011
2	Experimental Melanoma 01/2013 - 12/2011
1	Birth Weight (Birth Weights) 05/2022
1	Hypoglycemia (Reactive Hypoglycemia) 05/2022
1	Gestational Diabetes (Gestational Diabetes Mellitus) 05/2022
1	Polypoidal Choroidal Vasculopathy 01/2022
1	Ischemic Stroke 01/2022
1	Hemorrhagic Stroke 01/2022
1	Acute Promyelocytic Leukemia 01/2022
1	Vascular Diseases (Vascular Disease) 01/2022
1	Arteriovenous Fistula 01/2021
1	Fibrosis (Cirrhosis) 01/2021
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Leukocytosis (Pleocytosis) 12/2020
1	COVID-19 12/2020
1	Lymphopenia (Lymphocytopenia) 12/2020
1	Hyperglycemia 07/2020
1	Thyroid Neoplasms (Thyroid Cancer) 07/2020
1	Carcinoma (Carcinomatosis) 01/2019
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019
1	Chest Pain (Chest Pains) 01/2019
1	Hyperplasia 01/2019
1	Lung Diseases (Lung Disease) 01/2019
1	Lung Neoplasms (Lung Cancer) 01/2019

Drug/Important Bio-Agent (IBA)

7	Nicotinamide N-MethyltransferaseIBA 01/2021 - 01/2014
7	N-nitroso-N-methyltyramine (NNMT)IBA 01/2021 - 01/2014
6	Biomarkers (Surrogate Marker)IBA 12/2020 - 01/2016
4	Proteins (Proteins, Gene)FDA Link 12/2021 - 02/2013
4	MicroRNAs (MicroRNA)IBA 01/2016 - 01/2008
4	VaccinesIBA 01/2013 - 02/2011
3	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2021 - 01/2014
3	Small Interfering RNA (siRNA)IBA 01/2019 - 09/2009
3	Messenger RNA (mRNA)IBA 01/2019 - 01/2008
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2013 - 02/2011
3	AntigensIBA 01/2013 - 02/2011
2	Insulin (Novolin)FDA Link 05/2022 - 07/2020
2	CholesterolIBA 01/2022 - 12/2021
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 10/2018
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 01/2019
2	Fluorouracil (Carac)FDA LinkGeneric 01/2021 - 07/2016
2	Adenosine Triphosphate (ATP)IBA 11/2020 - 01/2020
2	Estrogen ReceptorsIBA 11/2020 - 01/2007
2	N(1)-methylnicotinamideIBA 07/2016 - 12/2014
2	DNA VaccinesIBA 12/2013 - 05/2011
2	Antiviral Agents (Antivirals)IBA 12/2013 - 05/2011
1	GlucokinaseIBA 05/2022
1	Retinaldehyde (Retinal)IBA 01/2022
1	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2022
1	LigandsIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022
1	CaspasesIBA 01/2022
1	N-methyladenosineIBA 01/2022
1	6-methyladenineIBA 01/2022
1	Arsenic Trioxide (Trisenox)FDA Link 01/2022
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2022
1	PlasticsIBA 01/2021
1	CollagenIBA 01/2021
1	CurcuminIBA 01/2021
1	Galectin 3 (LGALS3)IBA 01/2021
1	C-Reactive ProteinIBA 12/2020
1	ProcalcitoninIBA 12/2020
1	Ferritins (Ferritin)IBA 12/2020
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 11/2020
1	danaparoid (Orgaran)FDA Link 10/2020
1	Threonine (L-Threonine)FDA Link 07/2020
1	trans-crotonin (CTN)IBA 07/2020
1	Phosphopyruvate Hydratase (Enolase)IBA 07/2020
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 07/2020
1	Carcinoembryonic AntigenIBA 07/2020
1	Alanine (L-Alanine)FDA Link 07/2020
1	Hyaluronic Acid (Hyaluronan)IBA 05/2020
1	IntegrinsIBA 01/2019
1	CilengitideIBA 01/2019
1	methoxy poly(ethylene glycol)-poly(lactide)IBA 01/2019
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2019
1	CeramidesIBA 01/2019
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019
1	TroponinIBA 01/2019

Therapy/Procedure

3	Immunotherapy 01/2022 - 02/2011
3	Drug Therapy (Chemotherapy) 11/2020 - 01/2019
2	Therapeutics 05/2022 - 01/2022
2	Length of Stay 01/2020 - 06/2016
1	Vitrectomy 01/2022
1	Secondary Prevention 01/2022